Sucroferric Oxyhydroxide in Maintenance Hemodialysis: A Retrospective, Comparative Cohort Study.

ABSTRACT:

Rationale & objective

High pill burden associates with reduced phosphate-binder adherence among dialysis patients, contributing to elevated serum phosphorus levels. We compared the real-world effectiveness of sucroferric oxyhydroxide (SO) versus other phosphate binders in hemodialysis patients over 2 years.

Study design

Retrospective cohort study.

Setting & participants

Adult in-center hemodialysis patients prescribed 2 years of uninterrupted SO therapy (maintenance SO; n = 222) compared with patients who discontinued SO therapy (discontinued SO; n = 596) within 90 days of first prescription and switched to other phosphate binder(s) for 2 years.

Exposures

Phosphate binders.

Outcomes

Achievement of serum phosphorus levels ≤ 5.5 mg/dL, pill burden, and hos

SUBMITTER: Coyne DW 

PROVIDER: S-EPMC7380402 | biostudies-literature | 2020 May-Jun

REPOSITORIES: biostudies-literature