Development and Validation of Residual Kidney Function Estimating Equations in Dialysis Patients.

ABSTRACT:

Rationale & objective

Measurement of residual kidney function is recommended for the adjustment of the dialysis prescription, but timed urine collections are difficult and prone to errors. Equations to calculate residual kidney function from serum concentrations of endogenous filtration markers and demographic parameters would simplify monitoring of residual kidney function. However, few equations to estimate residual kidney function using serum concentrations of small solutes and low-molecular-weight proteins have been developed and externally validated.

Study design

Study of diagnostic test accuracy.

Setting & participants

823 Chinese peritoneal dialysis (PD) patients (development cohort) and 826 PD and hemodialysis patients from the Netherlands NECOSAD study (valid

SUBMITTER: Steubl D 

PROVIDER: S-EPMC7380427 | biostudies-literature | 2019 May-Jun

REPOSITORIES: biostudies-literature