Analysis of Oral Food Challenge Outcomes in IgE-Mediated Food Allergies to Almond in a Large Cohort.

ABSTRACT:

Background

Although almond specific IgE-mediated food allergies have traditionally been equated with other tree nut allergies, outcomes of oral food challenges to almond and the utility of clinical testing to predict IgE-mediated almond hypersensitivity are not well known.

Objective

To describe almond oral challenge outcomes and assess the predictive value of clinical testing.

Methods

A total of 603 almond challenges performed for 590 patients, aged 1 to 66 years, were analyzed from Massachusetts General Hospital allergy practices. Reactions were graded using the Niggemann and Beyer allergic reaction grading system and the Sampson 2006 National Institute of Allergy and Infectious Diseases anaphylaxis definition.

Results

Almond challenges included 545 passes (92

SUBMITTER: Virkud YV 

PROVIDER: S-EPMC7380558 | biostudies-literature | 2019 Sep - Oct

REPOSITORIES: biostudies-literature