The relationship between glycated haemoglobin levels and the risk of giant cell arteritis - a case-control study.

ABSTRACT:

Objectives

The EULAR core dataset for observational studies in GCA does not include glycated haemoglobin (HbA_1c). A multivariable score to stratify the pre-test probability of GCA also does not include HbA_1c. There have been contradictory reports about diabetes mellitus being a risk factor for GCA. We report the first study analysing the relationship of pre-diagnosis HbA_1c with the risk of GCA.

Methods

This was a single-centre retrospective case-control study conducted in Norfolk, UK. All GCA cases were diagnosed with imaging or biopsy. Each case was assigned two age- and sex-matched controls. The primary outcome measure was the glycaemic status (HbA_1c categorized into euglycaemia, pre-diabetes or diabetes mellitus) at diagnosis be

SUBMITTER: Mukhtyar C 

PROVIDER: S-EPMC7380559 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature