Association between topical beta-blockers and risks of cardiovascular and respiratory disease in patients with glaucoma: a retrospective cohort study.

ABSTRACT:

Objective

To determine if topical beta-blocker use is associated with increased risks of cardiovascular and respiratory diseases in patients with glaucoma.

Setting

A retrospective cohort analysis was conducted using the database from Taiwan's National Health Insurance programme.

Participants

In total, 12 336 newly diagnosed patients with glaucoma from January 2000 to December 2010 were included. The patients with glaucoma were subdivided into two cohorts according to whether they used topical beta-blockers or combination drugs (BBCDs).

Primary outcome measures

The study endpoints included pneumonia, acute respiratory failure, stroke and coronary artery disease (CAD). Univariable and multivariable Cox proportional hazards regression models were used to estimate

SUBMITTER: Chen HY 

PROVIDER: S-EPMC7380834 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature