Blood pressure and cognitive function across the eighth decade: a prospective study of the Lothian Birth Cohort of 1936.

ABSTRACT:

Objectives

We investigated the associations among blood pressure and cognitive functions across the eighth decade, while accounting for antihypertensive medication and lifetime stability in cognitive function.

Design

Prospective cohort study.

Setting

This study used data from the Lothian Birth Cohort 1936 (LBC1936) study, which recruited participants living in the Lothian region of Scotland when aged 70 years, most of whom had completed an intelligence test at age 11 years.

Participants

1091 members of the LBC1936 with assessments of cognitive ability in childhood and older adulthood, and blood pressure measurements in older adulthood.

Primary and secondary outcome measures

Participants were followed up at ages 70, 73, 76 and 79, and latent growth curve

SUBMITTER: Altschul D 

PROVIDER: S-EPMC7380861 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature