Systematic Identification of Target Genes for Cellular Morphology Engineering in Synechococcus elongatus PCC7942.

ABSTRACT: Cyanobacteria are serving as promising microbial platforms for development of photosynthetic cell factories. For enhancing the economic competitiveness of the photosynthetic biomanufacturing technology, comprehensive improvements on industrial properties of the cyanobacteria chassis cells and engineered strains are required. Cellular morphology engineering is an up-and-coming strategy for development of microbial cell factories fitting the requirements of industrial application. In this work, we performed systematic evaluation of potential genes for cyanobacterial cellular morphology engineering. Twelve candidate genes participating in cell morphogenesis of an important model cyanobacteria strain, Synechococcus elongatus PCC7942, were knocked out/down and overexpressed, respectively

SUBMITTER: Zhang M 

PROVIDER: S-EPMC7381316 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature