Cellular Organelles Reorganization During Zika Virus Infection of Human Cells.

ABSTRACT: Zika virus (ZIKV) is an enveloped positive stranded RNA virus belonging to the genus Flavivirus in the family Flaviviridae that emerged in recent decades causing pandemic outbreaks of human infections occasionally associated with severe neurological disorders in adults and newborns. The intracellular steps of flavivirus multiplication are associated to cellular membranes and their bound organelles leading to an extensive host cell reorganization. Importantly, the association of organelle dysfunction with diseases caused by several human viruses has been widely reported in recent studies. With the aim to increase the knowledge about the impact of ZIKV infection on the host cell functions, the present study was focused on the evaluation of the reorganization of three cell compo

SUBMITTER: Garcia CC 

PROVIDER: S-EPMC7381349 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature