Is Mother's Own Milk Lactoferrin Intake Associated with Reduced Neonatal Sepsis, Necrotizing Enterocolitis, and Death?

ABSTRACT:

Introduction

Lactoferrin (LF) is a protective protein present in milk with anti-infective and immune-modulating properties.

Objectives

The aim of this study was to determine the association of maternal LF intake and mother's own milk intake in the first 10 days of life on the prevention of late-onset sepsis (LOS), necrotizing enterocolitis (NEC), or death in the first 8 weeks of life in newborns with a birth weight <2,000 g.

Methods

A retrospective cohort study was conducted, with the exposure being the consumption of mother's own LF and mother's own milk in the first 10 days of life, and the outcome being LOS, NEC, or death during days 11 and 56 of life, analyzed by Cox regression.

Results

Two hundred and ninety-nine infants were enrolled, including 240 with h

SUBMITTER: Ochoa TJ 

PROVIDER: S-EPMC7381382 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature