Comorbidities and the risk of severe or fatal outcomes associated with coronavirus disease 2019: A systematic review and meta-analysis.

ABSTRACT:

Objectives

Existing findings regarding the relationship between comorbidities and the severity of coronavirus disease 2019 (COVID-19) are inconsistent and insufficient. The aim of this study was to evaluate the association between different comorbidities and the severity of COVID-19.

Methods

The PubMed, Embase, and Cochrane Library databases were searched to identify studies reporting the rates of comorbidities in COVID-19 patients with severe/fatal outcomes. Subgroup analyses were conducted according to disease severity and the country of residence. Odds ratios (OR) with 95% confidence intervals (CI) were pooled using random-effects models.

Results

A total of 34 eligible studies were identified. In patients with severe/fatal COVID-19, the most prevalent chronic comor

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC7381888 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature