Avenanthramide supplementation reduces eccentric exercise-induced inflammation in young men and women.

ABSTRACT:

Background

Avenanthramides (AVA) are a group of di-phenolic acids found only in oats and have shown antioxidant and anti-inflammatory effects in vitro and in vivo. Eccentric muscle contraction is intimately involved in rigorous exercise that activates systemic and local inflammatory responses. The objective of the study is to evaluate whether chronic AVA supplementation could attenuate peripheral inflammatory and immunological markers in human subjects in response to an acute bout of downhill running (DR).

Methods

Eleven male and thirteen female subjects voluntarily participated in this double-blinded, randomized controlled study and were randomly divided into AVA-supplemented (AVA) or control (C) groups. All subjects conducted a DR protocol at - 10% grade with an intensity

SUBMITTER: Zhang T 

PROVIDER: S-EPMC7382060 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature