Eimeria tenella Eimeria-specific protein that interacts with apical membrane antigen 1 (EtAMA1) is involved in host cell invasion.

ABSTRACT:

Background

Avian coccidiosis is a widespread, economically significant disease of poultry, caused by several Eimeria species. These parasites have complex and diverse life-cycles that require invasion of their host cells. This is mediated by various proteins secreted from apical secretory organelles. Apical membrane antigen 1 (AMA1), which is released from micronemes and is conserved across all apicomplexans, plays a central role in the host cell invasion. In a previous study, some putative EtAMA1-interacting proteins of E. tenella were screened. In this study, we characterized one putative EtAMA1-interacting protein, E. tenella Eimeria -specific protein (EtEsp).

Methods

Bimolecular fluorescence complementation (BiFC) and glutathione S-transferase (GST) fusion protein pull-d

SUBMITTER: Li C 

PROVIDER: S-EPMC7382093 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature