Variation in the use of radiotherapy fractionation for breast cancer: Survival outcome and cost implications.

ABSTRACT:

Background and purpose

Substantial variation in the adoption of hypofractionation for breast radiation therapy has been observed, despite the availability of consensus guidelines. This study aimed to investigate the variation in radiation therapy fractionation in breast cancer patients in New South Wales (NSW), Australia, and to estimate survival outcome and cost implications.

Materials and methods

This is a population-based cohort of patients who received radiation therapy for breast cancer (2009-2013), as captured in the NSW Central Cancer Registry. A logistic regression model was used to identify factors associated with fractionation type. Survival outcome was estimated using multivariable Cox proportional hazards model. Cost per treatment and potential cost saving associ

SUBMITTER: Batumalai V 

PROVIDER: S-EPMC7382346 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature