Frailty is an independent risk factor for recurrence and mortality following curative resection of stage I-III colorectal cancer.

ABSTRACT:

Aim

With population aging, the number of frail patients with colorectal cancer has increased. The Clinical Frailty Scale (CFS) is a validated tool for assessing frailty, and higher scores indicate worse clinical outcomes following cardiovascular procedures. This retrospective study aimed to examine preoperative frailty in relation to recurrence and mortality following curative resection of colorectal cancer.

Methods

We retrospectively analyzed data for 729 consecutive patients undergoing curative resection of stage I-stage III colon and rectal adenocarcinoma between January 2009 and December 2016. Frailty was assessed using the CFS: 1 (very fit) to 9 (terminally ill), and frailty was defined as CFS ≥ 4. Recurrence-free survival (RFS) and overall survival (OS) were compared b

SUBMITTER: Mima K 

PROVIDER: S-EPMC7382441 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature