Risk and Secondary Prevention of Stroke Recurrence: A Population-Base Cohort Study.

ABSTRACT:

Background and purpose

With recent advances in secondary prevention management, stroke recurrence rates may have changed substantially. We aim to estimate risks and trends of stroke recurrence over the past 2 decades in a population-based cohort of patients with stroke.

Methods

Patients with a first-ever stroke between 1995 and 2018 in South London, United Kingdom (n=6052) were collected and analyzed. Rates of recurrent stroke with 95% CIs were stratified by 5-year period of index stroke and etiologic TOAST (Trial of ORG 10172 in Acute Stroke Treatment) subtype. Cumulative incidences were estimated and multivariate Cox models applied to examine associations of recurrence and recurrence-free survival.

Results

The rate of stroke recurrence at 5 years reduced from 18% (9

SUBMITTER: Flach C 

PROVIDER: S-EPMC7382537 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature