Evaluation of an artificial intelligence clinical trial matching system in Australian lung cancer patients.

ABSTRACT:

Objective

The objective of this technical study was to evaluate the performance of an artificial intelligence (AI)-based system for clinical trials matching for a cohort of lung cancer patients in an Australian cancer hospital.

Methods

A lung cancer cohort was derived from clinical data from patients attending an Australian cancer hospital. Ten phases I-III clinical trials registered on clinicaltrials.gov and open to lung cancer patients at this institution were utilized for assessments. The trial matching system performance was compared to a gold standard established by clinician consensus for trial eligibility.

Results

The study included 102 lung cancer patients. The trial matching system evaluated 7252 patient attributes (per patient median 74, range 53-100) agains

SUBMITTER: Alexander M 

PROVIDER: S-EPMC7382632 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature