Using the Cochrane Central Register of Controlled Trials to identify clinical trial registration is insufficient: a cross-sectional study.

ABSTRACT:

Background

While conducting systemic reviews, searching for ongoing or unpublished trials is critical to address publication bias. As of April 2019, records of ongoing or unpublished randomized and/or quasi-randomized controlled trials registered in the International Clinical Trials Registry Platform (ICTRP) and ClinicalTrials.gov are available in the Cochrane Central Register of Controlled Trials (CENTRAL). These records registered in CENTRAL include studies published since the inception of ICTRP and ClinicalTrials.gov . Whether systematic reviewers can search CENTRAL to identify ongoing or unpublished trials instead of ICTRP and ClinicalTrials.gov is unknown.

Methods

This was a cross-sectional study. A consecutive sample of ongoing or unpublished studies published from Jun

SUBMITTER: Banno M 

PROVIDER: S-EPMC7382846 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature