Factors associated with first thrombosis in patients presenting with obstetric antiphospholipid syndrome (APS) in the APS Alliance for Clinical Trials and International Networking Clinical Database and Repository: a retrospective study.

ABSTRACT:

Objective

To evaluate the subsequent rate of thrombosis among women with obstetric antiphospholipid syndrome (Ob-APS) in a multicentre database of antiphospholipid antibody (aPL)-positive patients, and the clinical utility of the adjusted Global Antiphospholipid Syndrome Score (aGAPSS), a validated tool to assess the likelihood of developing new thrombosis, in this group of patients.

Design

Retrospective study.

Setting

The Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking Clinical Database and Repository.

Population

Women with Ob-APS.

Methods

Comparison of clinical and laboratory characteristics and measurement of aGAPSS in women with Ob-APS, with or without thrombosis, after initial pregnancy morbidity (PM).

Main out

SUBMITTER: de Jesus GR 

PROVIDER: S-EPMC7382947 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature