Influenza virus vaccination in children with nephrotic syndrome: insignificant risk of relapse.

ABSTRACT:

Background

Immunization with various vaccines is considered desirable for children with idiopathic nephrotic syndrome (NS) because of their high risk of severe infections. Vaccinations may precipitate relapses of NS, but there is no available data regarding inactivated influenza (flu) virus vaccines.

Methods

We retrospectively reviewed the medical records of children with NS who had received flu vaccines between 2002 and 2015. The day of flu vaccination was defined as day 0, and the period between the pre-vaccination and the post-vaccination days was defined as - X to + Y. The risk ratios and their 95% confidence intervals for NS relapse rate were estimated by generalized estimating equation (GEE) Poisson regression.

Results

A total of 104 pediatric patients received

SUBMITTER: Ishimori S 

PROVIDER: S-EPMC7383070 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature