Determinants of multidrug-resistant tuberculosis in Sao Paulo-Brazil: a multilevel Bayesian analysis of factors associated with individual, community and access to health services.

ABSTRACT:

Objective

Multidrug-resistant tuberculosis (MDR-TB) remains a serious public health problem worldwide. Accordingly, this study sought to identify individual, community and access to health services risk factors for MDR-TB.

Methods

Retrospective cohort of all TB cases diagnosed between 2006 and 2016 in the state of São Paulo. A Bayesian spatial hierarchical analysis with a multilevel design was carried out.

Results

It was identified that the history of previous TB treatment (Odds Ratios [OR]:13.86, 95% credibility interval [95% CI]:12.06-15.93), positive sputum culture test (OR: 5.26, 95% CI: 4.44-6.23), diabetes mellitus (OR: 2.34, 95% CI: 1.87-2.91), residing at a standard address (OR: 2.62, 95% CI: 1.91-3.60), positive sputum smear microscopy (OR: 1.74, 95% CI: 1.44

SUBMITTER: Arroyo LH 

PROVIDER: S-EPMC7383622 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature