Cold extremities in migraine: a marker for vascular dysfunction in women.

ABSTRACT:

Background and purpose

Migraine is recognized as a vascular risk factor, especially in women. Presumably, migraine, stroke and cardiovascular events share pathophysiological mechanisms. Self-reported cold extremities were investigated as a marker for vascular dysfunction in migraine. Secondly, it was hypothesized that suffering from cold extremities affects sleep quality, possibly exacerbating migraine attack frequency.

Methods

In this case-control study, a random sample of 1084 migraine patients and 348 controls (aged 22-65 years) from the LUMINA migraine cohort were asked to complete questionnaires concerning cold extremities, sleep quality and migraine.

Results

A total of 594 migraine patients and 199 controls completed the questionnaires. In women, thermal discomf

SUBMITTER: Linstra KM 

PROVIDER: S-EPMC7383740 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature