The global epidemiology of hepatitis E virus infection: A systematic review and meta-analysis.

ABSTRACT:

Background and aims

Hepatitis E virus (HEV), as an emerging zoonotic pathogen, is a leading cause of acute viral hepatitis worldwide, with a high risk of developing chronic infection in immunocompromised patients. However, the global epidemiology of HEV infection has not been comprehensively assessed. This study aims to map the global prevalence and identify the risk factors of HEV infection by performing a systematic review and meta-analysis.

Methods

A systematic searching of articles published in Medline, Embase, Web of science, Cochrane and Google scholar databases till July 2019 was conducted to identify studies with HEV prevalence data. Pooled prevalence among different countries and continents was estimated. HEV IgG seroprevalence of subgroups was compared and risk fac

SUBMITTER: Li P 

PROVIDER: S-EPMC7384095 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature