Transmission of viral hepatitis through blood transfusion in Sweden, 1968 to 2012.

ABSTRACT: IntroductionViral hepatitis remains a significant threat to transfusion safety, although largely mitigated by donor screening.AimOur objective was to estimate the past and present burden of transfusion transmission of all types of viral hepatitis (A to E) and to find undiagnosed infections with hepatitis C virus (HCV).MethodWe performed a retrospective cohort study using a database of the entire computerised transfusion experience of Sweden from 1968 to 2012 and linking it to a nationwide database of notifiable infections. We then used two independent statistical approaches. Firstly, we tracked recipients of blood from donors with confirmed viral hepatitis. Secondly, we computed a donor-specific risk score, defined as the difference between the observed and the expected number of HCV infec

SUBMITTER: Dahl V 

PROVIDER: S-EPMC7384284 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature