Ontology highlight
ABSTRACT:
SUBMITTER: Sereti I
PROVIDER: S-EPMC7384325 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Sereti Irini I Sheikh Virginia V Shaffer Douglas D Phanuphak Nittaya N Gabriel Erin E Wang Jing J Nason Martha C MC Roby Gregg G Ngeno Hellen H Kirui Fredrick F Pau Alice A Mican Joann M JM Rupert Adam A Bishop Rachel R Agan Brian B Chomchey Nitiya N Teeratakulpisarn Nipat N Tansuphaswadikul Somsit S Langat Deborah D Kosgei Josphat J French Martyn M Ananworanich Jintanat J Sawe Fredrick F
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20200701 3
<h4>Background</h4>Patients living with human immunodeficiency virus (PLWH) with low CD4 counts are at high risk for immune reconstitution inflammatory syndrome (IRIS) and death at antiretroviral therapy (ART) initiation.<h4>Methods</h4>We investigated the clinical impact of IRIS in PLWH and CD4 counts <100 cells/μL starting ART in an international, prospective study in the United States, Thailand, and Kenya. An independent review committee adjudicated IRIS events. We assessed associations betwe ...[more]