Optimal ^99mTc activity ratio in the single-day stress-rest myocardial perfusion imaging protocol: A multi-SPECT phantom study.

ABSTRACT:

Background

This investigation used image data generated by an anthropomorphic phantom to determine the minimal ^99mTc rest-stress activity concentration ratio (R) able to minimize the ghosting effect in the single-day stress-first myocardial perfusion imaging, using different positions of the perfusion defect (PD), scanners and reconstruction protocols.

Methods

A cardiac phantom with a simulated PD was imaged under different R using different gamma cameras and reconstruction algorithms. The residual activity from precedent stress administration was simulated by modeling effective half-times in each compartment of the phantom and assuming a delay of 3 hours between the stress and rest studies. The net contrast (NC) of the PD in the rest study was assessed for differ

SUBMITTER: Zoccarato O 

PROVIDER: S-EPMC7384561 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature