Novel histopathologic predictors for renal outcomes in crescentic glomerulonephritis.

ABSTRACT:

Introduction

Crescentic glomerulonephritis (CrGN) is a histologic feature of severe glomerular injury, clinically characterized by a rapid decline of renal function when not treated in a timely fashion. Factors associated with CrGN prognosis have not been thoroughly investigated. This study investigated the prognostic predictors of renal outcomes associated with CrGN, such as the histopathologic classification of anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, arteriosclerosis, and tertiary lymphoid organ (TLO) formation.

Methods

A total of 114 patients diagnosed with CrGN between 2010 and 2018 at two university-based hospitals has been retrospectively analyzed. Relationships between potential predictors and renal outcomes were analyzed using Cox p

SUBMITTER: Lim JH 

PROVIDER: S-EPMC7384637 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature