Photovoltaic Restoration of Central Vision in Atrophic Age-Related Macular Degeneration.

ABSTRACT:

Purpose

Loss of photoreceptors in atrophic age-related macular degeneration results in severe visual impairment, although some peripheral vision is retained. To restore central vision without compromising the residual peripheral field, we developed a wireless photovoltaic retinal implant (PRIMA; Pixium Vision, Paris, France) in which pixels convert images projected from video glasses using near-infrared light into electric current to stimulate the nearby inner retinal neurons.

Design

We carried out a first-in-human clinical trial to test the safety and efficacy of the prosthesis in patients with geographic atrophy (ClinicalTrials.gov identifier, NCT03333954).

Participants

Five patients with geographic atrophy zone of at least 3 optic disc diameters, no foveal light pe

SUBMITTER: Palanker D 

PROVIDER: S-EPMC7384969 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature