Cancer morbidity and mortality after pediatric solid organ transplantation-a nationwide register study.

ABSTRACT:

Background

The prevalence of malignancies after pediatric solid organ transplantation was evaluated in a nationwide study.

Methods

All patients who had undergone kidney, liver, or heart transplantation during childhood between the years 1982 and 2015 in Finland were identified. The inclusion criteria were age under 16 years at transplantation and age over 18 years at the last follow-up day. A total of 233 (137 kidney, 53 liver, and 43 heart) transplant recipients were enrolled. Controls (n = 1157) matched by the year of birth, gender, and hometown were identified using the Population Register Center registry. The cancer diagnoses were searched using the Finnish Cancer Registry.

Results

Altogether 26 individuals diagnosed with cancer were found, including 18 transplant

SUBMITTER: Enden K 

PROVIDER: S-EPMC7385020 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature