Technical Note: A step-by-step guide to Temporally Feathered Radiation Therapy planning for head and neck cancer.

ABSTRACT:

Purpose

Prior in silico simulations propose that Temporally Feathered Radiation Therapy (TFRT) may reduce toxicity related to head and neck radiation therapy. In this study we demonstrate a step-by-step guide to TFRT planning with modern treatment planning systems.

Methods

One patient with oropharyngeal cancer planned for definitive radiation therapy using intensity-modulated radiation therapy (IMRT) techniques was replanned using the TFRT technique. Five organs at risk (OAR) were identified to be feathered. A "base plan" was first created based on desired planning target volumes (PTV) coverage, plan conformality, and OAR constraints. The base plan was then re-optimized by modifying planning objectives, to generate five subplans. All beams from each subplan were imported ont

SUBMITTER: Parsai S 

PROVIDER: S-EPMC7386183 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature