Nucleosome structure and dynamics are coming of age.

ABSTRACT: Since the first high-resolution structure of the nucleosome was reported in 1997, the available information on chromatin structure has increased very rapidly. Here, we review insights derived from cutting-edge biophysical and structural approaches applied to the study of nucleosome dynamics and nucleosome-binding factors, with a focus on the experimental advances driving the research. In addition, we highlight emerging challenges in nucleosome structural biology.

SUBMITTER: Zhou K 

PROVIDER: S-EPMC7386248 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature