Methanobacterium formicicum as a target rumen methanogen for the development of new methane mitigation interventions: A review.

ABSTRACT: Methanobacterium formicicum (Methanobacteriaceae family) is an endosymbiotic methanogenic Archaean found in the digestive tracts of ruminants and elsewhere. It has been significantly implicated in global CH₄ emission during enteric fermentation processes. In this review, we discuss current genomic and metabolic aspects of this microorganism for the purpose of the discovery of novel veterinary therapeutics. This microorganism encompasses a typical H₂ scavenging system, which facilitates a metabolic symbiosis across the H₂ producing cellulolytic bacteria and fumarate reducing bacteria. To date, five genome-scale metabolic models (iAF692, iMG746, iMB745, iVS941 and iMM518) have been developed. These metabolic reconstructions revealed the cellular and me

SUBMITTER: Chellapandi P 

PROVIDER: S-EPMC7386643 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature