Treatment-free remission in chronic myeloid leukemia: the patient perspective and areas of unmet needs.

ABSTRACT: In CML, treatment-free remission (TFR) refers to having a stable deep molecular response without the need for ongoing tyrosine kinase inhibitor treatment. Whilst recommendations exist about the technical management of stopping and re-starting therapy, much is still unknown about the experiences of those considering and undertaking TFR. This study sought to obtain the patient perspective, identify areas of unmet needs and create recommendations for improvements. Fifty-six percent of patients reported fear or anxiety during treatment discontinuation, whereas only 7% of patients were asked if they needed psychological support during this period. Where patients re-initiated treatment; 59% felt scared or anxious, and 56% felt depressed. Twenty-six percent of re-initiated patients received psych

SUBMITTER: Sharf G 

PROVIDER: S-EPMC7387306 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature