Starch or Saline After Cardiac Surgery: A Double-Blinded Randomized Controlled Trial.

ABSTRACT:

Background

Despite decades of investigation, the balance of clinical risks and benefits of fluid supplementation with starch remain unresolved. Patient-centered outcomes have not been well explored in a "real-world" trial in cardiac surgery.

Objective

We sought to compare a starch-based fluid strategy with a saline-based fluid strategy in the cardiac surgery patient.

Design

A pragmatic blinded randomized controlled trial comparing starch-based with saline-based fluid strategy.

Setting

A large tertiary academic center in London Ontario between September 2009 and February 2011.

Participants

Patients undergoing planned, isolated coronary revascularization.

Measurements

Serum creatinine and patient weight were measured daily postoperatively.

Method

SUBMITTER: Nagpal AD 

PROVIDER: S-EPMC7388134 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature