Evaluation of pneumococcal meningitis clusters in Burkina Faso and implications for potential reactive vaccination.

ABSTRACT:

Background

To better understand how to prevent and respond to pneumococcal meningitis outbreaks in the meningitis belt, we retrospectively examined Burkina Faso's case-based meningitis surveillance data for pneumococcal meningitis clusters and assessed potential usefulness of response strategies.

Methods

Demographic and clinical information, and cerebrospinal fluid laboratory results for meningitis cases were collected through nationwide surveillance. Pneumococcal cases were confirmed by culture, polymerase chain reaction (PCR), or latex agglutination; strains were serotyped using PCR. We reviewed data from 2011 to 2017 to identify and describe clusters of ≥ 5 confirmed pneumococcal meningitis cases per week in a single district. We assessed whether identified clusters met t

SUBMITTER: Soeters HM 

PROVIDER: S-EPMC7388202 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature