The prevalence and mechanism of fluoroquinolone resistance in Escherichia coli isolated from swine farms in China.

ABSTRACT:

Background

It has been demonstrated that swine waste is an important reservoir for resistant genes. Moreover, the bacteria carrying resistant genes and originating from swine feces and wastewater could spread to the external environment. Fluoroquinolones (FQs) are widely used in livestock and poultry for the treatment of bacterial infection. However, resistance to FQs has increased markedly.

Results

In this study, swine feces and wastewater were sampled from 21 swine farms of seven provinces in China to investigate the prevalence of FQ resistance, including plasmid-mediated fluoroquinolone resistance (PMQR) genes and the occurrence of target mutations. All isolates showed moderate rate of resistance to norfloxacin (43.0%), ciprofloxacin (47.6%), ofloxacin (47.0%) and levoflo

SUBMITTER: Cheng P 

PROVIDER: S-EPMC7388466 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature