Albumin-bound paclitaxel and gemcitabine combination therapy in soft tissue sarcoma.

ABSTRACT:

Background

The evidence that albumin-bound paclitaxel (nab-paclitaxel) is safe and efficacious for the treatment of many types of malignant tumors is continuously increasing. However, the evidence and clinical data of nab-paclitaxel and gemcitabine in metastatic soft tissue sarcoma (STS) treatment are rare.

Methods

The clinical data of metastatic STS patients who received nab-paclitaxel/ gemcitabine chemotherapy between January 2019 and February 2020 were retrospectively analysed. All these patients were treated with nab-paclitaxel/ gemcitabine only after doxorubicin-based chemotherapy had failed. We evaluated the effectiveness and safety of nab-paclitaxel and gemcitabine in these patients.

Results

A total of 17 patients treated with nab-paclitaxel/ gemcitabine were e

SUBMITTER: Tian Z 

PROVIDER: S-EPMC7388541 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature