Age-Related Changes in Hair Shaft Protein Profiling and Genetically Variant Peptides.

ABSTRACT: Recent reports highlight possible improvements in individual identification using proteomic information from human hair evidence. These reports have stimulated investigation of parameters that affect the utility of proteomic information. In addition to variables already studied relating to processing technique and anatomic origin of hair shafts, an important variable is hair ageing. Present work focuses on the effect of age on protein profiling and analysis of genetically variant peptides (GVPs). Hair protein profiles may be affected by developmental and physiological changes with age of the donor, exposure to different environmental conditions and intrinsic processes, including during storage. First, to explore whether general trends were evident in the population at different ages, hair

SUBMITTER: Plott TJ 

PROVIDER: S-EPMC7388652 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature