Altered Cortical Functional Networks in Patients With Schizophrenia and Bipolar Disorder: A Resting-State Electroencephalographic Study.

ABSTRACT:

Background

Pathologies of schizophrenia and bipolar disorder have been poorly understood. Brain network analysis could help understand brain mechanisms of schizophrenia and bipolar disorder. This study investigates the source-level brain cortical networks using resting-state electroencephalography (EEG) in patients with schizophrenia and bipolar disorder.

Methods

Resting-state EEG was measured in 38 patients with schizophrenia, 34 patients with bipolar disorder type I, and 30 healthy controls. Graph theory based source-level weighted functional networks were evaluated: strength, clustering coefficient (CC), path length (PL), and efficiency in six frequency bands.

Results

At the global level, patients with schizophrenia or bipolar disorder showed higher strength, CC, a

SUBMITTER: Kim S 

PROVIDER: S-EPMC7388793 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature