Probiotics for induction of remission in Crohn's disease.

ABSTRACT:

Background

Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract, in which the pathogenesis is believed to be partly influenced by the gut microbiome. Probiotics can be used to manipulate the microbiome and have therefore been considered as a potential therapy for CD. There is some evidence that probiotics benefit other gastrointestinal conditions, such as irritable bowel syndrome and ulcerative colitis, but their efficacy in CD is unclear. This is the first update of a Cochrane Review previously published in 2008.

Objectives

To assess the efficacy and safety of probiotics for the induction of remission in CD.

Search methods

The following electronic databases were searched: MEDLINE (from inception to 6 July 2020), Embase (from inception

SUBMITTER: Limketkai BN 

PROVIDER: S-EPMC7389339 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature