Sexual dimorphism of gut microbiota at different pubertal status.

ABSTRACT:

Background

Accumulating evidence infer that gut microbiome-host relations are key mediators or modulators driving the observed sexual dimorphism in some disease onset and progression. To date, the sex-differences of gut microbiota at different pubertal status have not been reported.

Objective

To determine the characteristics of gut microbiota of both genders at different pubertal status.

Methods

Gut microbiota was analyzed in 89 Chinese participants aged 5-15 years. Participants were divided into pre-puberty and puberty groups for both male and female. The composition of gut microbiota was investigated by 16S rRNA-based metagenomics. Ecological representations of microbial communities were computed. The prediction of metagenomic functional content from 16S rRNA gene s

SUBMITTER: Yuan X 

PROVIDER: S-EPMC7390191 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature