OmicsON - Integration of omics data with molecular networks and statistical procedures.

ABSTRACT: A huge amount of atomized biological data collected in various databases and the need for a description of their relation by theoretical methods causes the development of data integration methods. The omics data analysis by integration of biological knowledge with mathematical procedures implemented in the OmicsON R library is presented in the paper. OmicsON is a tool for the integration of two sets of data: transcriptomics and metabolomics. In the workflow of the library, the functional grouping and statistical analysis are applied. Subgroups among the transcriptomic and metabolomics sets are created based on the biological knowledge stored in Reactome and String databases. It gives the possibility to analyze such sets of data by multivariate statistical procedures like Canonical Correlat

SUBMITTER: Turek C 

PROVIDER: S-EPMC7390260 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature