Bariatric Surgery for Monogenic Non-syndromic and Syndromic Obesity Disorders.

ABSTRACT:

Purpose of review

The global prevalence of obesity has increased rapidly over the last decades, posing a severe threat to human health. Currently, bariatric surgery is the most effective therapy for patients with morbid obesity. It is unknown whether this treatment is also suitable for patients with obesity due to a confirmed genetic defect (genetic obesity disorders). Therefore, this review aims to elucidate the role of bariatric surgery in the treatment of genetic obesity.

Recent findings

In monogenic non-syndromic obesity, an underlying genetic defect seems to be the most important factor determining the efficacy of bariatric surgery. In syndromic obesity, bariatric surgery result data are scarce, and even though some promising follow-up results have been reported, cautio

SUBMITTER: Vos N 

PROVIDER: S-EPMC7391392 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature