Influence of Processing Pipeline on Cortical Thickness Measurement.

ABSTRACT: In recent years, replicability of neuroscientific findings, specifically those concerning correlates of morphological properties of gray matter (GM), have been subject of major scrutiny. Use of different processing pipelines and differences in their estimates of the macroscale GM may play an important role in this context. To address this issue, here, we investigated the cortical thickness estimates of three widely used pipelines. Based on analyses in two independent large-scale cohorts, we report high levels of within-pipeline reliability of the absolute cortical thickness-estimates and comparable spatial patterns of cortical thickness-estimates across all pipelines. Within each individual, absolute regional thickness differed between pipelines, indicating that in-vivo thickness measureme

SUBMITTER: Kharabian Masouleh S 

PROVIDER: S-EPMC7391418 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature