Population structure, genetic diversity, and selective signature of Chaka sheep revealed by whole genome sequencing.

ABSTRACT:

Background

Chaka sheep, named after Chaka Salt Lake, are adapted to a harsh, highly saline environment. They are known for their high-grade meat quality and are a valuable genetic resource in China. Furthermore, the Chaka sheep breed has been designated a geographical symbol of agricultural products by the Chinese Ministry of Agriculture.

Results

The genomes of 10 Chaka sheep were sequenced using next-generation sequencing, and compared to that of additional Chinese sheep breeds (Mongolian: Bayinbuluke and Tan; Tibetan: Oula sheep) to explore its population structure, genetic diversity and positive selection signatures. Principle component analysis and a neighbor-joining tree indicated that Chaka sheep significantly diverged from Bayinbuluke, Tan, and Oula sheep. Moreover, t

SUBMITTER: Cheng J 

PROVIDER: S-EPMC7391569 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature