Microbiota assembly, structure, and dynamics among Tsimane horticulturalists of the Bolivian Amazon.

ABSTRACT: Selective and neutral forces shape human microbiota assembly in early life. The Tsimane are an indigenous Bolivian population with infant care-associated behaviors predicted to increase mother-infant microbial dispersal. Here, we characterize microbial community assembly in 47 infant-mother pairs from six Tsimane villages, using 16S rRNA gene amplicon sequencing of longitudinal stool and tongue swab samples. We find that infant consumption of dairy products, vegetables, and chicha (a fermented drink inoculated with oral microbes) is associated with stool microbiota composition. In stool and tongue samples, microbes shared between mothers and infants are more abundant than non-shared microbes. Using a neutral model of community assembly, we find that neutral processes alone explain the prev

SUBMITTER: Sprockett DD 

PROVIDER: S-EPMC7391733 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature