Transcriptome profiling and in silico detection of the antimicrobial peptides of red king crab Paralithodes camtschaticus.

ABSTRACT: Endogenous antimicrobial peptides (AMPs) are evolutionarily ancient factors of innate immunity, which are produced by all multicellular organisms and play a key role in their protection against infection. Red king crab (Paralithodes camtschaticus), also called Kamchatka crab, is widely distributed and the best known species of all king crabs belonging to the family Lithodidae. Despite their economic importance, the genetic resources of king crabs are scarcely known and no full-genome sequences are available to date. Therefore, analysis of the red king crab transcriptome and identification and characterization of its AMPs could potentially contribute to the development of novel antimicrobial drug candidates when antibiotic resistance has become a global health threat. In this study, we sequ

SUBMITTER: Yakovlev IA 

PROVIDER: S-EPMC7391757 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature