Human African trypanosomiasis: the current situation in endemic regions and the risks for non-endemic regions from imported cases.

ABSTRACT: Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense and caused devastating epidemics during the 20th century. Due to effective control programs implemented in the last two decades, the number of reported cases has fallen to a historically low level. Although fewer than 977 cases were reported in 2018 in endemic countries, HAT is still a public health problem in endemic regions until it is completely eliminated. In addition, almost 150 confirmed HAT cases were reported in non-endemic countries in the last three decades. The majority of non-endemic HAT cases were reported in Europe, USA and South Africa, due to historical alliances, economic links or geographic proximity to disease-endemic countries. Furthermore, with the implement

SUBMITTER: Gao JM 

PROVIDER: S-EPMC7391876 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature