Three-dimensional visualization of brain tumor progression based accurate segmentation via comparative holographic projection.

ABSTRACT: We propose a new optical method based on comparative holographic projection for visual comparison between two abnormal follow-up magnetic resonance (MR) exams of glioblastoma patients to effectively visualize and assess tumor progression. First, the brain tissue and tumor areas are segmented from the MR exams using the fast marching method (FMM). The FMM approach is implemented on a computed pixel weight matrix based on an automated selection of a set of initialized target points. Thereafter, the associated phase holograms are calculated for the segmented structures based on an adaptive iterative Fourier transform algorithm (AIFTA). Within this approach, a spatial multiplexing is applied to reduce the speckle noise. Furthermore, hologram modulation is performed to represent two different r

SUBMITTER: Abdelazeem RM 

PROVIDER: S-EPMC7392220 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature