Medical use of cocaine and perioperative morbidity following sinonasal surgery-A population study.

ABSTRACT:

Background

Topical cocaine is favoured by many surgeons for sinonasal surgery due to its superior vasoconstrictive and anesthetic properties. However, historical reports suggesting cocaine is associated with an increased risk of cardiac events have led many surgeons to turn to alternative topical medications. The objective of this study was to determine whether cocaine use during sinonasal surgery is associated with an increased risk of perioperative cardiac events and death.

Methods

We conducted a population-based analysis of patients undergoing sinonasal surgery from 2009-2016 using linked administrative health care data sets in Ontario, Canada. We compared patients treated at institutions that primarily use topical cocaine (exposed group) to those treated at institutions

SUBMITTER: MacNeil SD 

PROVIDER: S-EPMC7392254 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature