Distribution of hepatitis B virus genotypes in the general population of Myanmar via nationwide study.

ABSTRACT:

Background

Hepatitis B virus (HBV) infections are a severe health concern worldwide. HBV is a DNA virus with a rapid rate of mutation. Based on heterogeneity of the nucleotide sequence, the HBV strains are divided into nine genotypes, each with a characteristic geographical distribution. Identifying and tracking alterations of HBV genotypes is important in epidemiological and transmission studies, and contributes to predicting the risk for development of severe liver disease and response to antiviral treatment. The present study was undertaken to detect HBV genotypes and sub-genotypes in the general population of different states and regions in Myanmar.

Methods

In 2015, a total of 5547 adults of the general population, residing in seven states, seven regions and the Nay Pyi

SUBMITTER: Kyaw YY 

PROVIDER: S-EPMC7392661 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature